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分析了６４例老年及老年前期肾病患者的临床病理资料，并与儿童组及中青年组进行对比研究。结果表明，其临床表现以肾病综合征及持续性尿检异常最常见，约半数伴有肾功能异常，合并症及并发症多见。原发性肾小球疾病者占大多数，其中ＩｇＡ肾病最多见。与儿童组及中青年组相比，膜性肾病及膜增生性肾炎明显多见，微小病变少见，继发性者则以糖尿病肾病、肾淀粉样变较多见，疗效差。此外，肾小球硬化多见，肾小管间质病变较重亦为其病理特点。提示尽早肾活检及实施个体化治疗对老年及老年前期肾小球疾病患者尤为重要。
The clinical and pathological data of 64 elderly and elderly patients with early nephropathy were analyzed and compared with those of children and middle-aged and young people. The results showed that the most common clinical manifestations of nephrotic syndrome and persistent urinalysis, about half with renal dysfunction, complications and complications more common. Primary glomerular disease accounted for the majority, of which the most common IgA nephropathy. Compared with children group and middle-aged group, membranous nephropathy and membranous proliferative glomerulonephritis were more common, minor lesion was rare, secondary to diabetic nephropathy, renal amyloidosis more common, poor efficacy. In addition, more common glomerular sclerosis, tubulointerstitial lesions also for its pathological features. Prompt as soon as possible renal biopsy and the implementation of individualized treatment of elderly and elderly patients with glomerular disease is particularly important.