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目的了解妊娠期妇女在不同孕期血清铁蛋白(SF)、叶酸(FA)和25羟基维生素D(25OHD)检测的意义。方法运用化学发光免疫分析法检测150例作产前保健的孕妇(妊娠组)、55例无贫血症状健康妊娠妇女(对照2组)在不同孕期及55例健康体检合格的非妊娠妇女(对照1组)的SF、FA和25OHD含量。结果随着孕期的增加三项的含量都逐渐下降,与对照组相比,妊娠组早孕的SF、25OHD较低,差异具有统计学意义(P<0.05),FA比较差异无统计学意义(P>0.05),中、晚期的SF、FA和25OHD含量均比对照组低,差异具有统计学意义(P<0.01)。随着孕期的增加,SF和FA低下检出率逐渐升高,差异具有统计学意义(P<0.05)。结论检测妊娠期妇女在不同孕期SF、FA和25OHD含量可以对妊娠期贫血的防治提供帮助,保障母婴安全。
Objective To investigate the significance of serum ferritin (SF), folic acid (FA) and 25-hydroxyvitamin D (25OHD) in pregnant women during pregnancy. Methods 150 pregnant women with prenatal care (pregnancy group) and 55 healthy pregnant women without anemia (control group 2) were detected by chemiluminescence immunoassay in different pregnant women and 55 healthy non-pregnant women (control 1 Group) SF, FA and 25OHD content. Results Compared with the control group, the levels of SF and 25OHD in the pregnancy group were lower than those in the control group (P <0.05), and there was no significant difference in FA between the two groups (P > 0.05). The levels of SF, FA and 25OHD in the middle and late stages were lower than those in the control group, with statistical significance (P <0.01). With the increase of pregnancy, the detection rate of SF and FA was gradually increased, the difference was statistically significant (P <0.05). Conclusion Detection of SF, FA and 25OHD levels in pregnant women during pregnancy may help prevent and cure anemia during pregnancy and ensure the safety of mother and infant.