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目的：评估土黄连液外敷治疗糖尿病足溃疡的临床疗效。方法：65例糖尿病足溃疡Wagner分级法1-3级患者随机分为两组，其中对照组32例，溃疡创面采用1：5000呋喃西林外敷换药，每天一次；治疗组33例，溃疡创面采用土黄连液外敷换药，每天1次，两组均治疗30天，观察溃疡创面愈合情况。同时两组分别于治疗前、治疗后1周取创面分泌物行细菌培养，观察比较两组治疗后抑菌效果。结果：治疗组疗效显著，痊愈率及总有效率均优于对照组(P<0.05)，经治疗1周后治疗组抑菌率高于对照组(P<0.05)，差异均有统计学意义。结论：土黄连液有良好的抗菌、促进溃疡创面愈合的作用。“,”Objective To evaluate the effects of soil Coptis liquid in treating diabetic foot ulcer.Methods 65 patients with diabetic foot ulcers of Wagner Grade 1-3,who were randomly divided into treatment group(n=33)and control group(n=32).All the patients were changed fresh dressing once a day.The control group were given by 1:5000 furacilinum on wounds,while the treatment group were given by soil Coptis liquid.Results The effective rate of the treatment group was higher than that of the control group(P<0.05). After treatment for 1 weeks, the inhibition rate of the treatment group was higher than that of the control group(P<0.05).Conclusion Soil Coptis liquid has the effect of antibiosis,it can promot the healing of ulcer.