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为探索UK的安全有效剂量,我院将1988年3月～1991年4月间31例符合溶栓指征的AMI患者分为大剂量UK(100万u)组与中等剂量UK(50万u)组,对两组溶栓效果、预后及并发症进行比较。 1 病例选择与方法 1.1 病例选择及溶栓指征 (1)年龄≤70岁;(2)持续性胸痛>0.5h,静滴硝酸甘油无效;(3)发病时间6小时以内或在24小时心电图ST段仍呈单项曲线,没有病理性Q波;(4)心电图符合AMI的证据;(5)无溶栓禁忌症。符合上述溶栓指征的31例AMI患者按入院顺序分为两组:组Ⅰ16例,男14例,女2例。平均年龄50.9±8.9岁。梗塞部位:前壁3例,前
In order to explore the safe and effective dose of UK, 31 patients with AMI who were eligible for thrombolytic indications from March 1988 to April 1991 were divided into high-dose UK (1 million u) group and middle dose UK (500 thousand u ) Group, the two groups of thrombolytic effect, prognosis and complications were compared. 1 Case Selection and Methods 1.1 Case Selection and Thrombolytic Indication (1) Age ≤ 70 years; (2) Continuous chest pain> 0.5h, intravenous nitroglycerin ineffective; (3) onset time within 6 hours or 24 hours ECG ST segment is still a single curve, no pathological Q wave; (4) evidence of ECG consistent with AMI; (5) no thrombolytic contraindications. Thirty-one AMI patients who met the above-mentioned thrombolytic indications were divided into two groups according to hospital admission order: group Ⅰ 16 cases, 14 males and 2 females. The average age of 50.9 ± 8.9 years. Infarction site: anterior wall in 3 cases, before