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The flow ability, foam, and detergency performance of SOE-N-60 are introduced, the advantages of its application in the formulation of laundry beads are analyzed. Then, the formulation of laundry beads based on SOE-N-60 was developed. The results showed that SOE-N-60 has low foaming performance and excellent flow ability at low temperature, and it can maintain good liquidity of the mixed system, the laundry beads formulation has low foaming performance and its detergency meets the industry standards.