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为探索一种既消除眩晕又保存听力的治疗致残性眩晕的药物性迷路切除术，应用透明质酸－链霉素（ＨＡ－ＳＭ）圆窗灌注术治疗６例梅尼埃病（Ｍｅｎｉｅｒｅ病，ＭＤ）和４例迟发性内淋巴积水（ＤＥＨ）。结果：９例眩晕控制，８例听力不变或提高，７例耳鸣耳闭减轻或消失，前庭功能检测示眼震时间明显缩短（Ｐ＜０００１）。结论：ＨＡ－ＳＭ圆窗灌注术可选择性次全或完全破坏前庭功能，消除眩晕，保存听力，前庭功能代偿快，手术安全有效。
To explore a pharmacologic labyctomy for the treatment of disabling dizziness that avoids vertigo and preservation of hearing, six cases of Meniere’s disease (Meniere’s disease) were treated with round-window hyaluronic acid-streptomycin (HA-SM) , MD) and 4 cases of delayed endolymphatic hydrops (DEH). Results: 9 cases of dizziness control, 8 cases of hearing unchanged or increased, 7 cases of tinnitus auricle eased or disappeared, vestibular function test showed significantly shorter nystagmus time (P <0001). CONCLUSION: HA-SM round window perfusion can selectively and completely destroy the vestibular function, eliminate dizziness, preserve hearing, compensate the vestibular function quickly and safely and effectively.