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1970年Pinkus首先提出了巨细胞棘皮瘤(LCA)的概念。本病在临床上是一种轻度色素沉着及轻度过度角化损害,稍高出皮面,红色基底,损害直径约为5～10毫米。本文作者从34,000份皮肤病理标本中,诊断了38例LCA,说明它是比较常见的。标本均取自白人患者,年龄从28～89岁,平均59.94岁。LCA多见于女性,女∶男为26∶12。它好发于日光曝晒部位,面部尤其多见,占17例;其次,上肢12例,下肢4例,背部3例,躯干前部2例。38例原来的临床诊断:脂溢性疣18例,光化性角化病11例,基底细胞上皮瘤5例,雀斑4例。
In 1970 Pinkus first proposed the concept of giant cell acanthosis (LCA). The disease is clinically mild hyperpigmentation and mild hyperkeratotic lesions, slightly higher than the skin, red base, damage diameter of about 5 to 10 mm. The author of this article diagnosed 38 cases of LCA from 34,000 skin pathological specimens, indicating that it is more common. The specimens were taken from white patients and were aged from 28 to 89 years old, with an average of 59.94 years old. LCA is more common in women, and female: male is 26:12. It occurred in the sun exposure area, particularly in the face, accounting for 17 cases; followed by 12 cases of upper extremity, 4 cases of lower extremities, 3 cases of the back, 2 cases of the front of the trunk. 38 cases of the original clinical diagnosis: seborrheic fistula in 18 cases, 11 cases of actinic keratosis, basal cell epithelial tumor in 5 cases, 4 cases of freckles.