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乙胺碘呋酮(amiodarone)是治疗多种心律失常的药物。其副作用:甲状腺病变、神经病变、皮肤色素沉着及角膜病变等。但它所致晶体改变尚未见报道,作者首次报道了这一改变。检查对象为14例用其他药物治疗无效的顽固性心律失常患者,在旧金山一医院接受中～大剂量(600—800mg/日)乙胺碘呋酮治疗。治疗时间6～18个月,并在该院高血压病诊所选择同年龄有相似晶体变化的患者作对照。进行视力、裂隙灯、压平眼压计及扩瞳眼底检查。14人中,发现7人晶体于瞳孔区前囊下有小
Amiodarone is a drug used to treat a variety of arrhythmias. Side effects: thyroid disease, neuropathy, skin pigmentation and corneal disease. However, the crystal change it caused has not been reported, the authors reported for the first time this change. A total of 14 patients with refractory arrhythmias who were refractory to other medications were enrolled in a medium to large dose (600-800 mg / day) of amiodarone at a hospital in San Francisco. Treatment time 6 to 18 months, and in the hospital hypertensive clinic choose the same age with similar crystal changes in patients as a control. Visual acuity, slit lamp, flattened tonometer and dilation fundus examination. 14 people, found that seven people in the pupil before the lens capsule has a small capsule