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目的探讨利培酮治疗急性脑梗死所致精神与认知障碍的疗效。方法选取本院2012年3月至2012年12月的急性脑梗死所致精神障碍住院患者62例,予利培酮治疗,分别于治疗前及治疗后第2周末采用简明精神病量表(BPRS)及简易智能量表(MMSE)评价患者精神及认知功能。结果 BPRS评分较治疗前显著降低,对比具有显著差异(P<0.01),BPRS评分总有效率为74.2%,显效率为58.1%;MMSE评分较治疗前显著提高,对比具有意义(P<0.01)。结论利培酮对急性脑梗死所致精神障碍的治疗效果显著,且能改善认知功能.
Objective To investigate the efficacy of risperidone in the treatment of mental and cognitive disorders caused by acute cerebral infarction. Methods Sixty-two inpatients with mental disorders due to acute cerebral infarction from March 2012 to December 2012 in our hospital were treated with risperidone. Before and 2 weeks after treatment, the patients were enrolled in this study. Concise mental illness scale (BPRS) And simple intelligence scale (MMSE) to evaluate the patient’s mental and cognitive function. Results The BPRS score was significantly lower than that before treatment (P <0.01). The total effective rate of BPRS score was 74.2% and markedly effective rate was 58.1%. MMSE score was significantly higher than that before treatment (P <0.01) . Conclusions Risperidone has a significant therapeutic effect on mental disorders caused by acute cerebral infarction and can improve cognitive function.