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目的:探讨和分析将左旋甲状腺素片应用于妊娠合并甲状腺功能减退的安全性,以及它对妊娠结局的临床影响情况。方法:随机择选重庆市涪陵区妇幼保健院2010年12月至2016年6月,妇产科住院部接收的184例妊娠合并甲状腺功能减退孕妇。依据数字表法将孕妇实施分组治疗,即:对照组孕妇(92例)应用常规方法治疗,观察组孕妇(92例)应用左旋甲状腺素片治疗,并统计、对比和分析两组孕妇的临床治疗情况。结果:经过临床治疗,观察组孕妇的临床总有效率93.48%和正常自然分娩率71.74%均明显高于对照组孕妇59.78%,33.70%,均存在统计学意义(P<0.05)。结论:在妊娠合并甲状腺功能减退孕妇的临床诊疗中应用左旋甲状腺素片干预,其症状缓解迅速,临床效果显著,是一种安全有效、理想科学的临床治疗方法。
Objective: To investigate and analyze the safety of levothyroxine tablets in pregnancy complicated with hypothyroidism and its clinical effect on pregnancy outcome. METHODS: A total of 184 pregnant women with hypothyroidism who were admitted to the Inpatient Department of Obstetrics and Gynecology from December 2010 to June 2016 were randomly selected from Fuling District Maternal and Child Health Hospital of Chongqing. According to the digital table method, pregnant women were divided into groups. The control group of pregnant women (92 cases) were treated by conventional method. The pregnant women (92 cases) in the observation group were treated with levothyroxine tablets, and the clinical treatment of the two groups were statistically analyzed and compared Happening. Results: After clinical treatment, the clinical effective rate of 93.48% and normal spontaneous delivery rate of observation group were significantly higher than that of pregnant women (59.78%, 33.70%, P <0.05). Conclusion: The application of levothyroxine intervention in the clinical diagnosis and treatment of pregnant women with hypothyroidism in pregnancy, the rapid relief of symptoms, clinical effect is significant, is a safe and effective, ideal scientific clinical treatment.