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目的:探讨妥泰治疗神经痛的临床疗效。方法:选取32例各种神经痛病人,其中三叉神经痛20例,坐骨神经痛5例, 枕神经痛5例,中间神经痛2例。方法:开始剂量25mg/次,2次/日,以后每周增加50mg/d,直到300mg/d,维持6周。 疗效判定采用自身对照治疗前后记分法进行评定。结果: 疼痛完全控制5例占15.6%,显效7例占21.87%,有效12例占37.5%,治疗总有效率达75%。结论:妥泰治疗神经痛疗效高,安全可靠。
Objective: To investigate the clinical efficacy of topiramate in the treatment of neuralgia. Methods: 32 cases of various neuralgia patients were selected, including 20 cases of trigeminal neuralgia, 5 cases of sciatica, 5 cases of occipital neuralgia and 2 cases of intermediate neuralgia. Methods: The initial dose of 25mg / time, 2 times / day, after a weekly increase of 50mg / d until 300mg / d, for 6 weeks. The efficacy of self-control decision using the scoring method before and after assessment. Results: Complete control of pain was 15.6% in 5 cases, effective in 7 cases was 21.87%, effective in 12 cases was 37.5%, and total effective rate was 75%. Conclusion: Topotecan treatment of neuralgia has high efficacy, safe and reliable.