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前列腺素(PGs)和白细胞三烯(LTs)被认为在变应性炎症反应中起重要作用。阿司匹林过敏三联症常伴存鼻息肉,使人们怀疑前列腺素、白细胞三烯和其他花生四烯酸代谢产物可能与鼻息肉的发病机理有关。本研究是测定鼻息肉和鼻粘膜中的花生四烯酸代谢产物和前列腺素、白细胞三烯的浓度,以企阐明它们与鼻息肉发病学方面的关联。鼻息肉和鼻粘膜的样本由鼻息肉切除和鼻手术操作时取得,存于-70℃备用。将鼻息肉
Prostaglandins (PGs) and leukotrienes (LTs) are thought to play an important role in the allergic inflammatory response. Aspirin allergy triad often associated with nasal polyps, making people suspect prostaglandin, leukotrienes and other arachidonic acid metabolites may be related to the pathogenesis of nasal polyps. This study determined the concentrations of arachidonic acid metabolites and prostaglandins and leukotrienes in nasal polyps and nasal mucosa, and clarified their association with the pathogenesis of nasal polyps. Nasal polyps and nasal mucosa specimens were obtained from nasal polyps excision and nasal surgery and stored at -70 ° C until use. Will be nasal polyps