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对眼外伤后继发蜡样芽胞杆菌感染的6例严重眼内容炎作了分析和讨论,这些蜡样芽胞杆菌是从12例革兰氏阳性芽胞杆菌性眼内容炎中鉴定出来的。本文报道的6眼蜡样芽胞杆菌性眼内容炎中,5眼发展成全眼球炎,最终导致眼内容剜出或眼球摘除。蜡样芽胞杆菌是革兰氏阳性芽胞杆菌,可能通过细菌产生的外毒素致病。细菌一旦进入玻璃体内后,将会迅速地繁殖并破坏眼球组织。蜡样芽胞杆菌眼内感染的临床特点是起病急,暴发性发展,如不及时用有效的抗菌素治疗,包括玻璃体内注射敏感抗菌素,则其预后是很差的。根据蜡样芽胞杆菌性全眼球炎的临床特点作出早期诊断是很重要的,如能及时用庆大霉素、氯霉素、红霉素、氯林可霉素,以及联合采用玻璃体切割手术,可能使本病的结局改观。
Six cases of severe ocular inflammations secondary to ocular trauma with Bacillus cereus infection were analyzed and discussed, and the B. cereus was identified from 12 cases of Gram-positive bacillus intraocular inflammation. Of the 6 eyes of Bacillus cereus that were reported in this article, 5 developed full-blown inflammation that eventually led to eyeball removal or enucleation. Bacillus cereus is a gram-positive bacillus that may be pathogenic by exotoxins produced by bacteria. Once inside the vitreous, the bacteria will rapidly multiply and destroy the eyeball. The clinical characteristics of Bacillus cereus intraocular infection is the onset of acute and fulminant development, if not promptly treated with effective antibiotics, including intravitreal injection of sensitive antibiotics, the prognosis is poor. Early diagnosis based on the clinical features of Bacillus cereus whole-eye inflammation is very important, such as timely use of gentamicin, chloramphenicol, erythromycin, clindamycin, and the combination of vitrectomy surgery, May change the outcome of this disease.