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目的 研究强直性脊柱炎 (AS)患者血液流变学的变化。方法 对 5 2例AS患者和 5 0例健康成人分别进行血液流变学测定。包括红细胞压积、红细胞沉降率、纤维蛋白原、全血表观粘度值、血浆粘度值、红细胞和血小板电泳时间等指标的测定。结果 患者组红细胞压积、纤维蛋白原、全血表观粘度 (4S-1～ 2 0 0S-1)均明显增加 ,血浆粘度、红细胞电泳时间及血小板电泳时间均增加。结论 AS患者疼痛发作期血液流变学有明显改变 ,血液呈微凝态。
Objective To study the changes of hemorheology in patients with ankylosing spondylitis (AS). Methods Hemorheology was measured in 52 AS patients and 50 healthy adults. Including hematocrit, erythrocyte sedimentation rate, fibrinogen, whole blood apparent viscosity, plasma viscosity, erythrocyte and platelet electrophoresis time and other indicators of determination. Results The hematocrit, fibrinogen and whole blood apparent viscosity (4S-1 ~ 200S-1) were significantly increased, and the plasma viscosity, erythrocyte electrophoresis time and platelet electrophoresis time were all increased in patients. Conclusion The rheology of patients with AS during the onset of pain is significantly changed, and the blood is slightly coagulated.