苯二氮革类可分为短效(如去甲羟安定、氯羟安定、羟基安定和三唑苯二氮革)和长效(如利眠灵、安定、氯氮革和去甲安定)两类。这种分法是根据各药物的血浆半衰期而定的。短效苯二氮革类通常作为催眠药,而长效者却最好用于治疗慢性焦虑症。通常认为半衰期长的药物每日用药一次就足够了。这是根据临床效应与血浆浓度有直接相关的假设。 Benzodiazepines can be divided into short-acting (such as methotrexate, metoclopramide, hydroxyzepam and triazole benzodiazepines) and long-acting (such as liriling, diazepam, chlordiazepoxide and norebazepine) Two categories. This method is based on the plasma half-life of each drug. Short-acting benzodiazepines are commonly used as hypnotics, whereas long-acting ones are best used to treat chronic anxiety disorders. It is generally considered sufficient to use once-daily medications with long half-life. This is based on the assumption that clinical effects are directly related to plasma concentrations.