氨苄青霉素为半合成青霉素,属青霉素类,对革兰氏阴性菌如大肠杆菌、流感杆菌、伤寒杆菌等有较强的作用,其原型从肾脏和胆汁排泄,故多用于泌尿系统和胆道感染,或与其他抗生素如氨基甙类抗生素合用于各种严重感染,以增强疗效。临床上青霉素速发型变态反应发生率较高,甚至出现过敏性休克,故常引起医护人员重视,而迟发型反应往往易被忽视。现将我科1994年所见15例氨苄青霉素迟发型反应介绍如下。 Ampicillin is semi-synthetic penicillin, is a penicillin, Gram-negative bacteria such as Escherichia coli, influenza bacilli, Salmonella typhi and so have a strong role, the prototype from the kidneys and bile excretion, it is mostly used in urinary tract and biliary tract infections, Or with other antibiotics such as aminoglycoside antibiotics for a variety of serious infections, to enhance the efficacy. Clinically, the incidence of allergic reactions to penicillin rapid onset, and even anaphylactic shock, so often caused by medical staff attention, and delayed reactions are often easily overlooked. 15 cases of ampicillin delayed type reaction seen in our department in 1994 are as follows.