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1974年以来有些作者报告用别嘌呤醇治疗癫痫,该文自1988年研究了较多的病人。材料和方法 31例癫痫病人,平均年龄7岁10个月(4个月～22岁),癫痫病程平均为4年5个月(2个月～22年),均曾用过多种抗癫痫药(AEDs)治疗。仍每月发作1次～每日发作50次(平均2.4次/日)。31例中26例(84%)有中枢神经系统症状。观察时间:每天发作1次以上者观察1周,1周内发作1～6次者观察2周,1个月内发作1～3次者观察2个月。在原治疗基础上加用别嘌呤醇,开始剂量为
Some authors report on the treatment of epilepsy with allopurinol since 1974, and since 1988 more patients have been studied. Materials and Methods 31 cases of epilepsy patients, the average age of 7 years and 10 months (4 months to 22 years), epilepsy duration of an average of 4 years and 5 months (2 months to 22 years), have used a variety of anti-epileptic Drugs (AEDs) treatment. Still attack once a month ~ 50 episodes per day (average 2.4 times / day). Twenty-six of the 31 patients (84%) had central nervous system symptoms. Observation time: 1 episode per day for more than 1 week observation, 1 week to 1 to 6 times within 1 week were observed for 2 weeks, 1 month 1 to 3 times were observed for 2 months. On the basis of the original treatment plus allopurinol, the initial dose