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目的 探讨磁共振 (MR)和质子磁共振波谱 (MRS)在颞叶癫定位诊断中的作用。方法 15例经脑电图 (EEG)检查确诊为颞叶癫并接受手术治疗的顽固性颞叶癫患者进行MR和MRS检查 ,MR检查包括海马区域 ,MRS检查测定N 乙酰天门冬氨酸 (NAA)、肌酸 (Cr)及胆碱复合物 (Cho)的浓度并计算NAA/ (Cr+Cho)值。结果 MR检查发现 15例中海马硬化 11例 ,4例未发现异常 ;MRS检查 13例患者颞叶NAA/ (Cr+Cho)值异常 ,其中单侧异常 8例 ,双侧异常 5例 ,以患侧为重。两者结合可对 14例患者定位。结论 MR和MRS可分别从影像学和化学递质改变的角度为颞叶癫定位提供依据 ,两者结合可对颞叶癫进行定位诊断。
Objective To investigate the role of magnetic resonance (MR) and proton magnetic resonance spectroscopy (MRS) in the diagnosis of temporal lobe epilepsy. Methods Fifteen patients with refractory temporal lobe epilepsy diagnosed as temporal lobe epilepsy undergoing EEG examination underwent MR and MRS examinations. The MR examination included the hippocampus region. MRS was performed to detect N-acetyl-aspartate (NAA), creatine (Cr) and choline complex (Cho) were calculated and NAA / (Cr + Cho) values were calculated. Results In the MR examination, 11 cases of hippocampal sclerosis were found in 15 cases, and no abnormality was found in 4 cases. The MRA showed abnormality of the NAA / (Cr + Cho) in the temporal lobe, including 8 cases of unilateral abnormality and 5 cases of bilateral abnormalities Side is heavy. The combination of the two can be located in 14 patients. Conclusion MR and MRS can provide the basis for temporal lobe epilepsy localization from the perspective of imaging and chemical transmitter changes, and the combination of the two can be used to locate the temporal lobe epilepsy.