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由柯萨奇病毒A24变种(CA24v)引起的急性出血性结膜炎(AHC)在沙市出现首次流行后半年与1年(即1989年春、秋季),从城市居民中采集了423份血清,用微量中和试验作了CA24v中和抗体与特异性IgM的检测。春季中和抗体阳性率为37.9％,特异性IgM阳性率为3.3％;秋季为48.8％与6.7％,并从感冒样病人中分离到1株CA24v,提示1989年秋季又有一次CA24v的传播过程。在年龄分布上,秋季中各年龄组抗体阳性率已无明显差异,提示经一年多的传播扩散,各年龄组的免疫水平已趋于接近,达到50％左右,并预测近期内本地将不会有CA24v引起的AHC流行。
Acute haemorrhagic conjunctivitis (AHC) caused by the Coxsackievirus A24 variant (CA24v) was collected in the Shah City six months and one year after the first epidemic (ie spring and autumn 1989), 423 serum samples were collected from urban residents, Neutralization test was made for the detection of CA24v neutralizing antibodies and specific IgM. The positive rate of neutralizing antibody in spring was 37.9%, the positive rate of specific IgM was 3.3%, that in autumn was 48.8% and 6.7%, and one CA24v was isolated from cold-like patients, suggesting another CA24v transmission in autumn 1989 . In terms of age distribution, there was no significant difference in the positive rate of antibody in each age group in autumn, suggesting that after more than one year of spread, the immunization level of all age groups has approached 50%, and the local population will not There will be AHC epidemic caused by CA24v.