１ 临床资料患者男性，21岁，因2个月前误服有机磷农药，导致昏迷，抽搐等中毒症状，经抢救急性中毒症状消失。但一周后，出现双手、双足疼痛，麻木无力，呈进行性加重，致行走困难，不能持物。体格检查：双手大小鱼际肌、骨间肌明显萎缩，近端肌肉无萎缩，双下肢无肌肉萎缩， 1 Clinical data Male patients, 21 years old, 2 months ago due to accidentally take organophosphorus pesticides, resulting in coma, convulsions and other symptoms of poisoning, the symptoms of acute poisoning after treatment disappeared. However, a week later, his hands, his feet ached, his numbness was weak, his progress was aggravating, causing difficulty in walking and unable to hold things. Physical examination: hands size of the atresia muscle, interosseous muscle was significantly reduced, no proximal muscle atrophy, no muscle weakness in both lower extremities,