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目的:控制母婴垂直传播HBV、HIV、TP等病原菌的发生率,为规范产房操作程序,降低院内感染提供实验依据。方法:采用酶联免疫吸附(ELISA)方法检测产妇外周血、新生儿脐血中HBsAg,HIV1/2抗体;红细胞凝集法检测TPHA。结果:产妇外周血和新生儿脐血标本579份,HBsAg阳性率分别为本16.06%(93/579)和3.80(22/579),垂直感染率为23.66%(22/93);TP阳性率分别为1.38%(8/579)和0.52%(3/579),垂直感染率为37.50%(3/8);HIV阳性率均为0%。结论:母婴垂直传播病原菌的发生率高,须加强医院产房消毒管理制度,制定严谨的产房操作规程,防止医患人员院内感染。
Objective: To control the incidence of vertical transmission of HBV, HIV, TP and other pathogens in mother and infant, to provide experimental evidence for standardizing the procedure of delivery room and reducing nosocomial infection. Methods: HBsAg and HIV1 / 2 antibodies in peripheral blood of pregnant women and newborns were detected by enzyme linked immunosorbent assay (ELISA) and TPHA by erythrocyte agglutination. Results: The positive rates of HBsAg in maternal peripheral blood and neonatal cord blood samples were 16.06% (93/579) and 3.80 (22/579) respectively, and the vertical infection rate was 23.66% (22/93). The positive rates of TP 1.38% (8/579) and 0.52% (3/579) respectively. The vertical infection rate was 37.50% (3/8). The positive rate of HIV was 0%. Conclusion: The incidence of vertical transmission of pathogens in mother and infant is high. It is necessary to strengthen the disinfection management system in the hospital maternity ward, and to establish strict maternity ward rules to prevent nosocomial infections among doctors and patients.