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目的对16例TTV联合或重叠感染者进行临床研究。方法 TTV阳性患者均进行甲、乙、丙、丁、戊、庚型肝炎免疫标志物和各项生化项目检测。结果 16例感染者,与联合或重叠感染乙型肝炎率最高,占62.6％;其次是丁型肝炎18.8％,丙型肝炎6.2％,戊型肝炎6.2％,甲型肝炎6.2％。双重感染12例占75％,三重感染4例占25％。急性肝炎3例占18.8％,慢性肝炎2例占12.5％,肝硬化3例占18.8％。结论 TTV与乙型肝炎、丙型肝炎和丁型肝炎联合或重叠易形成慢性化,转变为肝硬化、肝癌机率增加,减少联合或重叠感染对肝炎防治将有重要意义。
Objective To study 16 patients with TTV combined or overlapping infection. Methods TTV positive patients were tested for A, B, C, D, E and G hepatitis immune markers and various biochemical projects. Results Among the 16 infected patients, the incidence of hepatitis B was 62.6% with combined or overlapping infection, followed by hepatitis B by 18.8%, hepatitis C by 6.2%, hepatitis E by 6.2% and hepatitis A by 6.2%. Twelve cases of infection accounted for 75%, triple infection in 4 cases accounted for 25%. 3 cases of acute hepatitis accounted for 18.8%, 2 cases of chronic hepatitis accounted for 12.5%, 3 cases of cirrhosis accounted for 18.8%. Conclusion TTV and hepatitis B, hepatitis C and hepatitis D combined or overlap easily form chronic, into cirrhosis, increased risk of liver cancer, reduce joint or overlapping infection of hepatitis prevention and treatment will be of great significance.