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应用免疫细胞化学ABC法对降钙素基因相关肽（CGRP）在大鼠纹状体边缘区内的分布以及与杏仁核、终纹床核等边缘系统结构之间的联系进行了研究。结果发现：（1）CGRP免疫阳性纤维在纹状体内存在于纹状体的中部和尾侧，位于尾壳核和苍白球之间，即相当于纹状体边缘区的部位，形成一条明显的背腹方向走行的带状。CGRP免疫阳性纤维分布越靠纹状体尾，则纤维越密集，且阳性带越宽；（2）在纹状体的最尾侧，除边缘区外，尾壳核的外侧缘也出现一条致密的阳性纤维带，与边缘区走向一致。并与边缘区的CGRP阳性纤维带之间存在较多的横向联系纤维；（3）纹状体边缘区的CGRP阳性纤维向背侧通过终纹与吻侧的终纹床核联系，向腹侧与杏仁核的CGRP阳性纤维相连，向尾侧和中脑黑质外侧部及其背外侧区的CGRP阳性胞体相连；（4）边缘区的CGRP阳性纤维主要与杏仁中央核相联系，少量与杏仁内侧核相联系；尾壳核外侧缘的CGRP阳性纤维也主要与杏仁中央核相联系。结果提示：CGRP阳性纤维在纹状体边缘区、杏仁核、终纹床核以及黑质背外侧区之间形成了一个相互联系的神经网络，纹状体边缘区与边缘系统之间存在密切的纤维联系。
Immunocytochemical ABC method was used to study the distribution of calcitonin gene-related peptide (CGRP) in the marginal division of rat striatum and its relationship with the marginal system structures such as amygdala, The results showed that: (1) CGRP immunoreactive fibers existed in the striatum in the middle and tail of the striatum, located between the caudate putamen and the globus pallidus, that is, the part corresponding to the marginal division of the striatum, forming an obvious Dorsal abdomen walking in the direction of the band. CGRP-positive immunofluorescence distribution more along the striatum tail, the more dense fibers, and the positive band width; (2) in the caudal striatum, in addition to the marginal zone, the lateral margin of the caudate putamen also a dense Of the positive fiber band, and the edge of the same direction. (3) The CGRP-positive fibers in the marginal zone of the striatum were connected to the dorsal side by the terminal striae and the kinetochore nucleus, CGRP-positive fibers in the amygdala were connected to CGRP-positive cells in the caudal and midbrain lateral substantia nigra and the dorsolateral zone. (4) CGRP-positive fibers in marginal zone were mainly associated with almond central nucleus, Nuclear; caudate putamen nucleus lateral CGRP-positive fibers are also mainly associated with the almond central nucleus. The results suggest that CGRP-positive fibers form an inter-related neural network between the striatum margins, the amygdala, the striation nucleus, and the substantia nigra dorsolateral regions. There is a close relationship between the marginal zone of the striatum and the limbic system Fiber connection.