肝脂肪变性严重危害人类健康,可以进一步发展为脂肪性肝炎,肝纤维化,肝硬化,甚至肝癌。肝纤维化作为其中一个重要环节,具有特殊意义,因为肝纤维化是一个可逆的病理过程。有报道提出脂肪变性与肝纤维化密切相关[1-5]。1H-MRS能无创地定量检测肝内脂肪含量,有望为肝纤维化的病情进展、临床治疗及 Hepatic steatosis, a serious risk to human health, can further develop into steatohepatitis, liver fibrosis, cirrhosis, and even liver cancer. Liver fibrosis as one of the important links is of special significance because liver fibrosis is a reversible pathological process. It has been reported that steatosis and liver fibrosis are closely related [1-5]. 1H-MRS can quantitatively detect intrahepatic fat content noninvasively and is expected to be the progression of liver fibrosis, clinical treatment and