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环磷酰胺(CTX)腹腔给药(iP)可抑制小鼠脾脏T细胞及B细胞的增殖,使其免疫功能下降;可抑制小鼠骨髓有核细胞的形成,使其造血功能下降;可抑制小鼠超氧化物歧化酶(SOD)合成系统,使其血清SOD活性下降、扶正抗癌冲剂(FKG)灌胃给药(ig),可改善小鼠被CTX所抑制的上述各项指标,提示该冲剂可减轻CTX所致小鼠机体的损害.
Cyclophosphamide (CTX) administered intraperitoneally (iP) inhibited the proliferation of T cells and B cells in the spleen of mice, and decreased its immune function; it inhibited the formation of bone marrow nucleated cells in mice and decreased their hematopoietic function; The superoxide dismutase (SOD) synthesis system in mice reduces the serum SOD activity, and administration of Fuzheng Kangai Granules (FKG) by intragastric administration (ig) can improve the above indicators inhibited by CTX in mice. The granules can reduce the body damage caused by CTX.