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本文对111例经病理检查证实的膀胱移行细胞癌作了血型的回顾性调查。发现其中 A 型和 AB 型血型明显高于正常人群的 A 型和 AB 型的血型分布(P<0.01及P<0.05)。并且发现膀胱癌中 A 型血的恶性程度高(P<0.05)。O型血的膀胱癌恶性程度低(P<0.01)。ABO(H)血型物质是红细胞表面的一种多酪物质,具有明显的抗原性。它是由遗传决定的.近年研究表明,在人体多种细胞上可查见ABO(H)抗原的存在,并可以通过这种抗原的缺失作为膀胧癌预后的一项指标.目前国际国内采用特异性细胞粘附法和免疫过氧化酶法检测手段。这种方法尽管在不断完善,但方法较复杂,容易出现误差.因此仍不能广泛地应用于临床.膀胧移行细胞癌与血型相互关系的研究,对于膀胧癌的预后及流行病学方面有一定的意义。国外已有报导,但有无种族差异还是一个值得探讨的间题.本文对经病理证实的111例膀胧移行细胞癌与其血型分布作一回顾性调查研究.
In this paper, 111 cases of bladder transitional cell carcinoma confirmed by pathology were retrospectively investigated. The blood type distributions of Type A and Type AB were significantly higher than those in normal population (P <0.01 and P <0.05). A type of blood in bladder cancer was found to have a high degree of malignancy (P <0.05). O-type blood bladder cancer is less malignant (P <0.01). ABO (H) blood group substance is a multi-cheese material on the surface of erythrocytes with obvious antigenicity. It is genetically determined in recent years, studies have shown that in a variety of human cells can be found on the presence of ABO (H) antigen, and can be used as an indicator of the prognosis of bladder cancer by the loss of this antigen.At present, both internationally and domestically Specific cell adhesion and immunoperoxidase detection methods. Although this method continues to improve, but the method is more complex and prone to error.Therefore, it is still not widely used in clinical.Biliary transitional cell carcinoma and blood type of relationship between the prognosis and epidemiology of bladder cancer have A certain meaning. It has been reported in foreign countries, but whether there is racial difference or not is a question worth exploring.This paper makes a retrospective investigation of 111 cases of idiopathic transitional cell carcinoma of the bladder confirmed by pathology.