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目的探讨异丙酚联合尼卡地平降低神经介入治疗性脑血管痉挛的临床效果。方法选取行神经介入治疗的98例患者作为研究对象,采用随机数字表法分为两组,每组49例。实验组采用异丙酚联合尼卡地平治疗,对照组采用异丙酚与硝酸甘油联合治疗,观察两组总有效率、神经痉挛时间及前脑中动脉收缩峰流速。结果实验组总有效率高于对照组,差异有统计学意义(P<0.05);实验组神经痉挛时间低于对照组,差异有统计学意义(P<0.05);实验组前脑中动脉收缩峰流速低于对照组,差异有统计学意义(P<0.05)。结论异丙酚联合尼卡地平降低神经介入治疗性脑血管痉挛的临床效果显著,值得临床推广应用。
Objective To investigate the clinical effect of propofol combined with nicardipine in lowering the severity of neurological interventional cerebrovascular spasm. Methods A total of 98 patients undergoing neuro interventional therapy were divided into two groups (n = 49 in each group) by random number table. The experimental group was treated with propofol combined with nicardipine. The control group was treated with propofol combined with nitroglycerin. The total effective rate, the time of neurospastic spasm and the contraction peak velocity of the anterior cerebral artery were observed. Results The total effective rate of the experimental group was higher than that of the control group (P <0.05). The time of neurospasticity in the experimental group was lower than that of the control group (P <0.05) The peak velocity was lower than that of the control group, the difference was statistically significant (P <0.05). Conclusion Propofol combined with nicardipine reduce neurological interventional treatment of cerebral vasospasm clinical effect is significant, worthy of clinical application.