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目的探讨急性脑血管病患者发生感染的危险因素及感染对卒中患者预后的影响。方法对入选的850例急性脑血管患者根据是否感染分为两组,评估两组患者出院时巴氏指数(BI)、改良的Rankin量表评分(mRS)和减少的NIHSS百分数,出院后6个月随访病死率及BI、mRS。结果住院期间感染者298例,无感染者552例,感染组年龄明显大于无感染组(P<0.01),住院时间明显长于无感染组(P<0.05),出院6个月时BI均低于无感染组(P<0.01);出院6个月时减少的NIHSS百分数明显低于无感染组(P<0.01),mRS明显高于无感染组(P<0.01);随访时病死率明显高于无感染组(P<0.01)。结论年龄为脑卒中后发生感染的危险因素,并发感染不仅影响急性脑血管患者的神经功能恢复,且影响卒中后病死率。
Objective To investigate the risk factors of infection in patients with acute cerebrovascular disease and the influence of infection on the prognosis of stroke patients. Methods A total of 850 patients with acute cerebrovascular disease were divided into two groups based on whether they were infected or not. The Pa-Chi index (BI), Modified Rankin Scale (mRS), and the percentage of NIHSS decreased at discharge were evaluated. After discharge, 6 Monthly follow-up mortality and BI, mRS. Results 298 cases were infected during hospitalization, 552 cases were not infected. The infection group was significantly older than non-infected group (P <0.01), hospitalization time was significantly longer than that of non-infected group (P <0.05), BI was lower than 6 months after discharge (P <0.01). The percentage of NIHSS decreased at 6 months after discharge was significantly lower than that of non-infected group (P <0.01) and mRS was significantly higher than that of non-infected group (P <0.01) No infection group (P <0.01). Conclusions Age is a risk factor for infection after stroke. Complicated infection not only affects the recovery of neurological function in patients with acute cerebrovascular disease, but also affects the post-stroke mortality.