论文部分内容阅读
目的了解北京、新疆库尔勒(南疆)不同地区、性别、民族其成人胃食管反流病(GERD)、反流性食管炎(RE)的检出率及幽门螺杆菌(Hp)感染的情况,以期指导临床治疗。方法2000年7至12月,对北京、库尔勒两地有上消化道症状患者778例,进行胃镜、病理检查及快速尿素酶试验,部分患者还进行了24h食管pH动态监测和13C呼气试验。结果(1)北京地区汉族、库尔勒地区汉族和维族GERD检出率分别为6.4%、13.7%和25.5%(P<0.01);RE检出率分别为3.1%、6.6%和15.7%(P<0.01)。(2)北京地区汉族、库尔勒地区汉族和维族男性GERD检出率分别为6.5%、12.9%和25.0%(P<0.01),RE检出率分别为4.5%、9.7%和25.0%(P<0.01);女性GERD检出率分别为6.4%、14.4%和26.3%(P<0.05),RE检出率分别为1.3%、3.3%和0%(P>0.05)。(3)北京地区汉族、库尔勒地区汉族、维族GERD患者Hp感染率分别为20.0%、24.0%和23.1%(P>0.05);RE患者Hp感染率分别为23.5%、25.0%和25.0%(P>0.05)。结论北京和库尔勒地区不同民族、性别的GERD、RE的检出率均有差异,以后者为高,而其GERD、RE患者的Hp感染率差异无统计学意义。
Objective To investigate the prevalence of Helicobacter pylori (H.pylori) and detection of gastroesophageal reflux disease (GERD) and reflux esophagitis (RE) in different regions, sexes and ethnic groups in Beijing and Korla (southern Xinjiang) In order to guide clinical treatment. Methods From July to December 2000, 778 cases of upper gastrointestinal symptoms were observed in Beijing and Korla. Gastroscopy, pathological examination and rapid urease test were performed. Some patients also had 24h esophageal pH dynamic monitoring and 13C breath test. Results (1) The detection rates of GERD were 6.4%, 13.7% and 25.5% respectively in Han and Korla districts in Beijing (P <0.01). The detection rates of RE were 3.1%, 6.6% and 15.7% respectively (P < 0.01). (2) The detection rates of GERD were 6.5%, 12.9% and 25.0% (P <0.01) in Han and Korla districts of Beijing and 4.5%, 9.7% and 25.0% respectively (P < 0.01). The detection rate of GERD in women was 6.4%, 14.4% and 26.3% respectively (P <0.05). The detection rate of RE was 1.3%, 3.3% and 0% respectively (P> 0.05). (3) The prevalence of Hp infection in Han and Uygur nationality Han and Uygur in Beijing was 20.0%, 24.0% and 23.1%, respectively (P> 0.05). The prevalence of Hp infection in RE patients was 23.5%, 25.0% and 25.0% respectively > 0.05). Conclusions The detection rates of GERD and RE in different nationalities and genders in Beijing and Korla are all different, the latter are high, but there is no significant difference in the Hp infection rate between GERD and RE patients.