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目的:观察应用改良负压封闭引流(VSD)技术治疗糖尿病足的效果。方法:将糖尿病足40例患者随机分为对照组和治疗组。对照组应用传统VSD技术治疗,治疗组应用改良VSD技术治疗,即在VSD敷料中增加一根冲洗管,经冲洗管每日1次注入呋喃西林500 ml和表皮生长因子30 ml,30 min后关闭冲洗管,开启负压。于治疗10 d后开启创面,比较两组创面愈合率、肉芽生长情况评分、堵管率以及患者住院时间和住院费用等。结果:治疗组创面愈合率[(35.3±4.4)%]和肉芽生长情况评分[(2.9土0.8)分]明显高于对照组[分别为(20.4±3.9)%和(2.1±0.5)分,P<0.05)],堵管率、住院费用和住院时间[0、(48.6±4.6)d,(8.7±1.8)万元]显著低于对照组[15.0%,(64.6±5.5)d,(10.0士2.1)万元,P<0.05]。结论:改良VSD技术较传统VSD技术更能促进糖尿病足肉芽组织生长,促进创面愈合,降低住院费用,缩短住院时间,是治疗糖尿病足的有效方法。
Objective: To observe the effect of modified negative pressure closed drainage (VSD) on diabetic foot. Methods: 40 diabetic patients were randomly divided into control group and treatment group. The control group was treated with traditional VSD technique. The treatment group was treated with modified VSD technique. That is, an irrigation tube was added to the VSD dressing. Nitrofurazone 500 ml and epidermal growth factor 30 ml were infused into the irrigation tube once daily for 30 minutes and then rinsed off Tube, open the negative pressure. After 10 days of treatment, the wounds were opened. The wound healing rate, granulation growth score, occlusion rate, hospital stay and hospitalization expenses of the two groups were compared. Results: The wound healing rate [(35.3 ± 4.4)%] and granulation growth score (2.9 ± 0.8) in treatment group were significantly higher than those in control group [(20.4 ± 3.9)% and (2.1 ± 0.5) (48.6 ± 4.6) d, (8.7 ± 1.8) million] were significantly lower than those in the control group [15.0%, (64.6 ± 5.5) d, (P <0.05) and the rate of hospitalization and hospital stay 10.0 persons 2.1) million, P <0.05]. Conclusion: Compared with the traditional VSD technique, the modified VSD technique can promote the growth of diabetic foot granulation tissue, promote wound healing, reduce the cost of hospitalization and shorten the length of hospital stay. It is an effective method to treat diabetic foot.