目的　探讨上消化道 Dieulafoy病的诊断和治疗方法。方法　回顾性分析自 1993- 0 1～ 2 0 0 2 - 0 1收治的 13例 Dieulafoy病的临床资料。结果　 Dieulafoy病发生于胃底 7例 ,胃体近贲门小弯侧 3例 ,大弯侧 1例 ,十二指肠球部 1例 ,十二指肠降部 1例。主要表现为突发间歇性大量呕血、黑便和休克。 13例均通过急诊胃镜检查确诊 ,其中术后病理证实 2例。13例均行内镜下止血治疗 ,止血 11例 ,2例胃底 Dieulafoy病镜下止血失败转外科手术。结论　出血后尽快急诊胃镜检查是确诊本病的首选方法。治疗上可先行内镜下止血治疗 ,内镜止血后仍反复出血 ,特别是病灶位于胃底者 ,应及时转外科手术 Objective To investigate the diagnosis and treatment of upper gastrointestinal Dieulafoy disease. Methods The clinical data of 13 patients with Dieulafoy disease were retrospectively analyzed from 1993 to 2001-2002. Results Dieulafoy’s disease occurred in 7 cases of gastric fundus, 3 cases of lesser curvature on the side of gastric body, 1 case on the large curved side, 1 case of duodenal bulb and 1 case of descending part of duodenum. Mainly intermittent intermittent massive hematemesis, melena and shock. Thirteen cases were confirmed by emergency endoscopy, of which 2 cases were confirmed by pathology. Thirteen patients underwent endoscopic hemostasis, hemostasis in 11 cases, and 2 cases of fundula Dieulafoy’s disease undergoing hemostasis failure to surgery. Conclusion Emergency gastroscopy as soon as possible after bleeding is the first choice for the diagnosis of this disease. Treatment may be the first endoscopic treatment of hemostasis, endoscopic hemostasis is still repeated bleeding, especially lesions located in the fundus who should be promptly transferred to surgery