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目的:观察中药联合卡托普利和倍他乐克治疗轻、中度充血性心力衰竭的疗效。方法:将150例患者随机分为3组,A组单用中药治疗上组单用西药卡托普利加倍他乐克,C组中西药联合应用;3组均在用药后3周和3个月分别观察心功能各项指示。结果:(1)心功能总有效率A组为72%,B组为86%,C组为94%。(2)超声心动图左室舒张末期内径C组较A、B两组明显缩小(P<0.05)。(3)射血分数C组比A、B两组有显著提高(P<0.05)。(4)24h动态心电图C组室性早搏数比A、B组显著减少(P<0.05)。结论:中药联合卡托普利加倍他乐克联合应用提高了轻、中度充血性心力衰竭的疗效。
Objective: To observe the efficacy of traditional Chinese medicine combined with captopril and metoprolol in the treatment of mild to moderate congestive heart failure. Methods: One hundred and fifty patients were randomly divided into three groups. Group A was treated with traditional Chinese medicine only with captopril plus metoprolol, and group C with western medicine. The three groups were treated with three weeks and three Month were observed various indications of cardiac function. Results: (1) The total effective rate of heart function was 72% in group A, 86% in group B and 94% in group C. (2) The left ventricular end-diastolic diameter of group C was significantly smaller than that of group A and B in echocardiography (P <0.05). (3) The ejection fraction in group C was significantly higher than that in groups A and B (P <0.05). (4) 24h dynamic ECG group C premature ventricular contractions than A, B group was significantly reduced (P <0.05). Conclusion: The combination of traditional Chinese medicine and captopril plus metoprolol improves the curative effect of light and moderate congestive heart failure.