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内皮细胞 (Endothelialcells ,EC)是供、受者细胞间最早接触的部位 ,也是最早被受者免疫系统所识别的供体细胞。它对细胞因子具有高度反应性 ,并表达与淋巴细胞配体相互作用的多种分子。研究表明 ,淋巴细胞与EC之间相互作用是启动包括同种异体急、慢性排斥
Endothelial cells (ECs) are the earliest contact sites between donor and recipient cells, and are also the earliest donor immune system recognized donor cells. It is highly reactive to cytokines and expresses a variety of molecules that interact with lymphocyte ligands. Studies have shown that the interaction between lymphocytes and EC is initiated including allogenic acute and chronic rejection