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目的:研究探讨结核感染T细胞斑点试验(T-SPOT.TB)对疑似结核病患者的临床诊断价值。方法:选择开平市中心医院2014年3月至2016年3月疑似结核病患者97例,进行T-SPOT.TB检测,分别与血清结核抗体(38k D-Ig G)、结核菌素纯蛋白衍化物(PPD)、抗酸杆菌涂片结果作比较,观察其检验的灵敏度与特异性。结果:四种临床常用检查方法中,T-SPOT.TB灵敏度仅次于抗酸杆菌涂片检测,T-SPOT.TB的灵敏度和特异性与38k D-Ig G.PPD比较,差异有统计学意义,Z=-1.8257。结论:T-SPOT.TB对疑似结核病患者临床诊断的灵敏度与特异性均较高。
Objective: To study the clinical diagnostic value of T-SPOT.TB in patients with suspected tuberculosis. Methods: Ninety-seven patients with suspected TB were selected from Central Hospital of Kaiping City from March 2014 to March 2016, and T-SPOT.TB was used to detect the levels of serum TB antibody (38k D-Ig G), tuberculin pure protein derivative (PPD), acid-fast bacilli smear results for comparison, observe the sensitivity and specificity of its test. Results: The sensitivity of T-SPOT.TB was second only to smear of acid-fast bacilli in the four kinds of clinical tests. The sensitivity and specificity of T-SPOT.TB were compared with that of 38k D-Ig G.PPD Meaning, Z = -1.8257. Conclusion: The sensitivity and specificity of T-SPOT.TB in the diagnosis of suspected tuberculosis patients are high.