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通过离体实验观察了实验性获得性膜原位葡聚糖在变形链球菌Ｓ．ｍｕｔａｎｓ和Ｓ．ｓｏｂｒｉｎｕｓ附着牙面过程中的作用。结果表明：两菌具有相似的产生ＧＴＦ和原位葡聚糖的能力，但两菌附着量和附着率的差别较大。在有蔗糖和ＧＴＦ存在时，Ｓ，ｓｏｂｒｉｎｕｓ的附着率明显高于Ｓ．ｍｕｔａｎｓ．提示原位葡聚糖在Ｓ．ｓｏｂｒｉｎｕｓ的附着中起重要作用，Ｓ、ｓｏｂｒｉｎｕｓ主要以蔗糖依赖性机制定居牙面，而Ｓ．ｍｕｔａｎｓ主要以蔗糖非依赖性机制定居牙面。
Experimental Acquired In Situ Dextran in Streptococcus mutans S was observed by in vitro experiments. mutans and S. sobrinus attached to the role of tooth surface process. The results showed that the two bacteria had the similar ability to produce GTF and in situ dextran, but the difference between the two bacteria ’s attachment rate and attachment rate was larger. In the presence of sucrose and GTF, S, sobrinus attachment rate was significantly higher than S. mutans. Prompt in situ dextran in S. sobrinus plays an important role in the attachment, S, sobrinus mainly succulent-dependent mechanism of settlement of the tooth surface, Mutans colonize the tooth surface mainly in a sucrose-independent manner.