溃疡病人常出现各种细胞免疫和体液免疫障碍,如循环的T 细胞含量降低、辅助活性和抑制活性失衡、IgA 缺乏、IgM 水平上升、淋巴浆细胞组织浸润等。本文目的是阐明胃和十二指肠溃疡在恶化期和临床缓解期继发性免疫不足的特点。检查86例缓解期和恶化期溃疡病病人,其中61例十二指肠溃疡、25例胃溃疡,分疤痕形成和无疤痕形成两个亚型,均不伴有可以增高免疫指标的其它疾病.检查结果发现在溃疡病恶化期T 淋巴细胞含量增加,十二指肠溃疡病人尤为明显。两组病人活性T 细 Ulcer patients often appear a variety of cellular and humoral immune disorders, such as decreased circulating T cell content, ancillary activity and inhibitory activity imbalance, IgA deficiency, IgM levels, lymphoplasmacytic tissue infiltration and so on. The purpose of this article is to elucidate the characteristics of secondary immunodeficiency in gastric and duodenal ulcers during periods of exacerbation and clinical remission. Twenty-six patients with remission and exacerbation of ulcer disease were examined, of which 61 had duodenal ulcer, 25 had gastric ulcer, and had no scar formation. There were no other diseases that could increase the immune index. Examination results found that in the deterioration of ulcer disease T lymphocytes increased, especially in patients with duodenal ulcer. Two groups of patients with active T fine