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近年来 ,通过对肿瘤转移机制的广泛研究 ,发现细胞外基质 (ｅｘｔｒａｃｅｌｌｍａｔｒｉｘ ,ＥＣＭ)在肿瘤的浸润与转移过程中起着关键性的作用。基质金属蛋白酶 (ｍａｔｒｉｘｍｅｔａｌｌｏｐｒｏｔｅｉｎａｓｅｓ ,ＭＭＰｓ)通过对ＥＣＭ的降解而促进癌细胞对周围组织的浸
In recent years, extensive research on the mechanism of tumor metastasis has revealed that extracellular matrix (ECM) plays a key role in the process of tumor invasion and metastasis. Matrixmetalloproteinases (MMPs) promote the digestion of cancer cells into the surrounding tissues through the degradation of ECM