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作者研究了27例(报告5例,复习文献22例)成年后起病的慢性粘膜皮肤念珠菌病伴胸腺瘤患者的临床、病理学及免疫学特征.其中男性12例,女性15例,均在34~71岁发生皮肤、爪甲和粘膜的念珠菌感染.19例念珠菌病的开始早于胸腺瘤诊断平均3年.常伴发于胸腺瘤的疾病亦见于本文病例,包括:重症肌无力8例;肌炎3例;低丙种球蛋白血症3例;骨髓或循环血液成分疾患8例(再障、粒细胞减少、恶性贫血等).皮肤毛发异常(脱发、皮肤白斑、剥脱性红皮病)4例.在胸腺瘤病理资料完整的20例中,9例属良性,其中6例为女性;11例属恶性,
The authors studied the clinical, pathological and immunological features of chronic mucocutaneous candidiasis with thymoma in 27 patients (5 reported and 22 reviewed), including 12 males and 15 females, all of whom Candida infections of the skin, claw, and mucosa occur at ages 34 to 71. The onset of candidiasis in 19 patients was earlier than the diagnosis of thymoma for an average of 3 years, and the disease often associated with thymoma was also seen in this case, including myasthenia gravis 8 cases of weakness; 3 cases of myositis; 3 cases of hypogammaglobulinemia; 8 cases of bone marrow or circulatory blood component disorders (aplastic anemia, neutropenia, pernicious anemia, etc.) Skin abnormal hair (hair loss, leukoplakia, exfoliation Erythroderma) in 4 cases.In the thymoma complete pathological data of 20 cases, 9 cases are benign, of which 6 cases were female; 11 cases were malignant,