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目的 :了解抗菌药物使用现状 ,为临床合理用药提供资料。方法 :统计住院病人对 14种抗菌药物药敏试验结果并与其他已知结果比较 ,用限定日剂量 (DefinedDailyDose ,DDD)计算抗菌药物的消耗 ,结合药敏结果和抗菌药消耗量的日DDD数 (DDDs/d)分析抗菌药物使用现状。结果 :院内菌对环丙沙星敏感率较其它已知结果高 ,对青霉素类、氨基糖苷类抗菌药敏感率低。环丙沙星、青霉素、庆大霉素、克林霉素的日消耗DDDs值分别居第 1～ 4位。结论 :环丙沙星、头孢菌素类、红霉素等药物的使用较为合理。氨基糖苷类、青霉素类、克林霉素使用存在不合理现象。
Objective: To understand the current status of antimicrobial use and provide information for clinical rational drug use. Methods: The hospitalized patients were tested for the antimicrobial susceptibility test results of 14 antimicrobial agents and compared with other known results. Definitive Daily Dose (DDD) was used to calculate the consumption of antibiotics, combined with the daily DDDs of drug sensitivity and antibacterial drug consumption. (DDDs/d) Analyze the status of antimicrobial use. Results: The susceptibility rate of ciprofloxacin in the hospital was higher than other known results, and the sensitivity to penicillins and aminoglycosides was low. The daily consumption of ciprofloxacin, penicillin, gentamycin, and clindamycin ranked first to fourth in DDDs. Conclusion: The use of ciprofloxacin, cephalosporins, erythromycin and other drugs is more reasonable. The use of aminoglycosides, penicillins, and clindamycin is unreasonable.