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为探讨Ⅰ~Ⅱ期乳腺癌保守手术组织间插植配合根治性放射治疗的方法、疗效和美容效果,对Ⅰ期1例,Ⅱ期7例共8例早期乳腺癌保守术后组织间插植配合根治性放射治疗的效果进行临床观察研究。全部病例均于术后1个月内接受根治性放射治疗。放射治疗范围包括病侧乳腺、胸壁、内乳区以及腋窝和锁骨上淋巴结引流区。组织间插植于乳腺、胸壁外照射开始1~2周后进行,靶区范围包括手术疤痕及其周围15~2cm乳腺组织。随访10个月~5年余,全部病例健在。3年和5年生存率均达100%,无不良反应,未见局部复发及远处转移征象,并有良好的保留乳房、保持美容、保持功能状态和提高生存质量的效果。认为Ⅰ~Ⅱ期乳腺癌保守手术组织间插植配合根治性放射治疗,是能取代根治手术的一种可靠有效的治疗方法,符合Ⅰ~Ⅱ期的早期乳腺癌病人应给予保留乳房的治疗。
To explore the methods, efficacy, and cosmetic results of conservative radiotherapy for I-II stage breast cancer implantation combined with radical radiotherapy, 1 case of stage I, 7 cases of stage II, and 8 cases of early postoperative breast cancer after conservative tissue implantation Clinical observation studies were conducted in conjunction with the effectiveness of radical radiation therapy. All cases were treated with radical radiation therapy within 1 month after surgery. The scope of radiation therapy included the diseased side breast, chest wall, inner breast area, and drainage area of axillary and supraclavicular lymph nodes. Interplanting was performed between 1 to 2 weeks after irradiation in the mammary gland and chest wall. The scope of the target area included surgical scars and 1 to 5 cm of mammary tissue around them. Followed up for 10 months to 5 years, all cases were alive. The 3-year and 5-year survival rates were 100%, no adverse reactions, no local recurrence and distant metastasis signs, and good retention of breasts, maintaining beauty, maintaining functional status and improving the quality of life. It is considered that the conservative surgical intervention of I-II stage breast cancer combined with radical radiotherapy is a reliable and effective treatment that can replace radical surgery. Patients with stage I-II early breast cancer should be treated with reserved breasts.