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目的:探讨和分析米力农与西地兰治疗婴幼儿重症肺炎合并心力衰竭的疗效。方法:选取64例于2012年03月-2013年09月在我院接受治疗的婴幼儿重症肺炎合并心力衰竭患儿为研究对象,采取数字标记法将上述选取对象随机分成米力农组和西地兰组,每组均32例,两组均给予平喘、止咳、镇静、吸氧以及抗感染等常规对症治疗,米力农组患儿同时给予米力农进行治疗,西地兰组患儿也给予西地兰进行治疗,观察两组患者治疗前后症状变化情况及心电图检查变化。结果:在采取上述方案治疗下,米力农组32例患儿治疗效果为显效、有效、无效的人数依次为28例、3例和1例,总治疗有效率为96.87%;西地兰组32例患儿治疗效果为显效、有效、无效的人数依次为27例、3例和2例,总治疗有效率为93.75%;两组间上述指标对比无显著性差异(P<0.05),而西地兰组在症状改善时间上明显优于米力农组,两组间该项指标对比有显著性差异(P<0.05)。结论:米力农和西地兰对婴幼儿重症肺炎合并心力衰竭均有很好的治疗效果,均具备较高的安全性,但西地兰在纠正或改善体征及大部分临床症状上优于米力农,但米力农在缓解患儿烦躁情绪等症状上优于西地兰,因此在临床上应依据患儿的实际临床表现采取不同的方式进行治疗,必要时可以联合两种药物对患儿进行综合治疗。
Objective: To investigate and analyze the efficacy of milrinone and cedilanil in the treatment of infantile severe pneumonia complicated with heart failure. Methods: Sixty-four children with severe pneumonia complicated with heart failure undergoing pediatric treatment in our hospital from March 2012 to September 2013 were enrolled in this study. The selected subjects were randomly divided into Milrinone and West Diran group, 32 cases in each group, both groups were given conventional asthma, cough, sedation, oxygen and anti-infectives and other conventional symptomatic treatment, Milinong children treated with Milrinone at the same time, cedilanid Children were also given cedilanid treatment, observation of two groups of patients before and after treatment of symptoms and ECG changes. Results: Under the above-mentioned regimen, the treatment effect of 32 children in Milinong group was markedly effective, effective and ineffective followed by 28 cases, 3 cases and 1 case, the total effective rate was 96.87%; the cedilanid group There were 27 cases, 3 cases and 2 cases, the total effective rate was 93.75%. There was no significant difference between the two groups (P <0.05) Cedilanid group was significantly better than Milian group in symptom improvement time, and there was significant difference between the two groups (P <0.05). Conclusion: Both milrinone and cedilanid have good therapeutic effects on severe pneumonia complicated with heart failure in infants and young children, both of which have higher safety, but cedilanidin is superior to the correction or improvement of signs and most clinical symptoms Milrinone, but Milrinone in children with irritability and other symptoms relieve cedilanid, so in clinical should be based on the actual clinical manifestations of children take a different approach to treatment, if necessary, can be combined with two drug pairs Children with comprehensive treatment.