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利巴韦林是广谱抗病毒药,目前在临床广泛应用。利巴韦林氯化钠注射液制备及临床应用方面已有报道~([1])。但其制备过程中活性炭对利巴韦林含量有影响。本文探讨了活性炭用量对利巴韦林氯化钠注射液中利巴韦林含量的影响以及不同pH值时活性炭对利巴韦林含量的影响。1仪器与试剂7530G型分光光度计(惠普上海分析仪器有限公司);pHS-3B型数显酸度计(江苏电分析仪器厂);利巴韦林(河南
Ribavirin is a broad-spectrum antiviral and is currently widely used clinically. Ribavirin sodium chloride injection preparation and clinical application has been reported ~ ([1]). However, the activated carbon has an impact on the ribavirin content in the preparation process. This article explored the effect of activated carbon on the ribavirin content in ribavirin sodium chloride injection and the effect of activated carbon on ribavirin content at different pH values. 1 instruments and reagents 7530G spectrophotometer (HP Shanghai Analytical Instruments Co., Ltd.); pHS-3B digital acidity meter (Jiangsu Electrical Analysis Instrument Factory); ribavirin (Henan