快速诊断和及时有效治疗恶性疟,特别是抗药性恶性疾,仍是目前减少发病率和死亡率的最佳选择。作者通过对尼日利亚恶性疟患者原虫乳酸脱氢酶(pLDH)活性测定,进而与治疗药物、疗效、原虫密度、病程和再燃等诸多因素分析比较,认为pLDH是今后疟疾诊断、疗效判定以及流行病学调查中有极高潜力的指标。 Rapid diagnosis and timely and effective treatment of falciparum malaria, especially drug-resistant malignant disease, remain the best choice for reducing morbidity and mortality. Based on the analysis of protozoa lactate dehydrogenase (pLDH) activity in patients with falciparum malaria in Nigeria and further analysis of various factors such as drug therapy, efficacy, protozoa density, duration of disease and rebound, pLDH is considered as the future malaria diagnosis, efficacy evaluation and epidemiology There are very high potential indicators in the survey.