Calyculin A induces prematurely condensed chromosomes without histone H1 phosphorylation in mammalia

来源 :生物化学进展(英文) | 被引量 : 0次 | 上传用户：aoli668

【摘要】

：

It is shown here that one can induce prematurely condensed chromosomes (PCCs) in G1-phase human (HeLa) and mouse (FT210) cells by treating them with the protein

【作者】

：

James R. Paulson Erica R. Vand

【机构】

：

DepartmentofChemistry

【出处】

：

生物化学进展(英文)

【发表日期】

：

2013年3期

【关键词】

：

MITOSIS CHROMOSOME Condensation HISTONES Protein PHOSPHATASES Mitosis Chromosome

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It is shown here that one can induce prematurely condensed chromosomes (PCCs) in G1-phase human (HeLa) and mouse (FT210) cells by treating them with the protein phosphatase inhibitor calyculin A. However, histone H1 is not phosphorylated in these G1-PCCs.

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Calyculin A induces prematurely condensed chromosomes without histone H1 phosphorylation in mammalia

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