应用ＥＬＩＳＡ检测各类人群８２２例血清抗－ＨＧＶ，对５６例抗－ＨＧＶ阳性及１４例抗－ＨＧＶ阴性患者血清应用ＰＴ－ｎＰＣＲ检测ＨＧＶ－ＲＮＡ。结果：ＨＧＶ－Ｍ阳性率肝病组（３７９０％）显著高于肺结核组（１３４０％）和献血员组（７３５％），Ｐ＜００１，三者均显著高于自然人群组（１４０％），Ｐ＜００１；肝病组、肺结核组具有随年龄增长呈递增趋势；自然人群组以２９～３０岁年龄段为高；肝病组男性显著高于女性（Ｐ＜００５），该组男女分别高于其他各组（Ｐ＜００１）；肝病组各临床类型均显著高于自然人群组（Ｐ＜００１）。５６例抗－ＨＧＶ阳性患者ＨＧＶ－ＲＮＡ阳性４５例（８０４％），１４例抗－ＨＧＶ阴性ＨＧＶ－ＲＮＡ阳性５例（３５７％）。认为①本地区存在ＨＧＶ感染，其感染率以肝病组最高，自然人群组以青壮年为高；②ＨＧＶ可与甲～戊肝炎病毒重叠感染；③非甲－戊型肝炎中的ＨＧＶ感染只是一种病因，尚有其他病毒感染；④ＨＧＶ持续感染可能导致肝硬化和肝细胞癌；⑤检测抗－ＨＧＶ对筛查ＨＧＶ感染有一定的价值 Serum anti-HGV was detected in 822 cases of all kinds of people by ELISA, and HGV-RNA was detected by PT-nPCR in 56 cases of anti-HGV positive and 14 cases of anti-HGV negative. Results: The positive rate of HGV-M in liver disease group (3790%) was significantly higher than that in pulmonary tuberculosis group (1340%) and donated blood group (735%), P <001, Group (140%), P <001; liver disease group, pulmonary tuberculosis group showed an increasing trend with age; natural population age group 29 to 30 years old; liver disease group was significantly higher than the male (P <005). The male and female in this group were higher than those in other groups (P <001). The clinical types in liver disease group were significantly higher than those in the natural group (P <001). Among the 56 anti-HGV positive patients, 45 were HGV-RNA positive (804%) and 14 were anti-HGV negative (57%). It is considered that ① HGV infection exists in this area, with the highest infection rate in liver disease group and high in young people in natural population; ②HVV may overlap with hepatitis A and E virus; ③HGV infection in non-A-hepatitis E is only one Etiology, there are other viral infections; ④HVV persistent infection may lead to cirrhosis and hepatocellular carcinoma; ⑤ detection of anti-HGV screening of HGV infection has some value