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目的:观察分析手术切除联合辨证施治治疗66例喉癌临床疗效。方法:从2009年1月至2014年1月来院就诊的喉癌患者中选取66例,根据患者的不同病变部位来确定手术方式,并观察每位患者手术疗效。术后所有患者均进行中医辨证分型治疗,7 d为1个疗程。结果:所有患者术后恢复用口进食,喉部分切除患者的发音都得以恢复正常。其中有53例是施行喉部分切除术,占所有患者的80.30%,喉部分切除术拔管的有56例,占全部病例的84.85%。III期和IV期患者,喉部分切除的有29例,占全部病例的43.94%,所有喉癌患者1年生存率为93%,3年生存率为86.7%,5年生存率为67.7%。III期和IV期患者,实施喉部分切除和全喉切除手术患者的生存率差异无统计学意义(P>0.05)。结论:喉癌患者选择手术切除联合术后辅助中医辨证施治能够保留喉部的全功能,可以延长生命,提高生命质量。
Objective: To observe and analyze the clinical efficacy of surgical resection and syndrome differentiation in the treatment of 66 cases of laryngeal cancer. Methods: From January 2009 to January 2014, 66 cases of laryngeal cancer patients admitted to hospital were enrolled in this study. The surgical modalities were determined according to the different lesion sites of the patients and the curative effect of each patient was observed. All patients underwent TCM syndrome differentiation treatment, 7 days for a course of treatment. Results: All patients recovered with oral diet, and patients with partial laryngectomy returned to normal. Among them, 53 cases performed partial throat excision, accounting for 80.30% of all patients. Fifty-six cases were extubated, accounting for 84.85% of all cases. In stage III and IV patients, 29 cases were treated by partial laryngectomy, accounting for 43.94% of all cases. The 1-year survival rate was 93%, the 3-year survival rate was 86.7%, and the 5-year survival rate was 67.7%. There was no significant difference in survival between stage III and IV laryngectomy patients undergoing partial laryngectomy and total laryngectomy (P> 0.05). Conclusion: The surgical treatment of laryngeal cancer combined with postoperative adjuvant TCM syndrome differentiation can preserve the full function of the larynx, prolong life and improve the quality of life.