论文部分内容阅读
目的 :探讨 T3 期扩大喉部分切除和喉全切除术的疗效。方法 :于 1984年 1月至 1996年 5月对 112例 T3 期喉癌的临床资料进行回顾性分析 ,其中行扩大喉部分切除术 4 8例 (单纯手术 2 9例 ,手术加放疗 19例 ) ;喉全切除术 6 4例 (单纯手术 39例 ,手术加放疗法 2 5例 )。结果 :喉部分切除术组和喉全切除术组 3年和 5年生存率分别为 77.1%、6 6 .7%和 97.7%、71.1% ;各组单纯手术和手术加放疗的 3年和 5年生存率比较 ,喉部分切除组分别为 75.7%、6 5.0 %和 78.9%、6 9.2 % ;喉全切除组分别为81.2 %、71.4 %和 76 .0 %、70 .6 % ,各组 3年和 5年生存率均无显著性差异 (P>0 .0 5)。结论 :T3 期喉癌只要掌握好喉部分切除术的适应证 ,其疗效与喉全切除术接近 ;术后放疗不能减少局部和颈部癌复发的危险
Objective: To investigate the effect of partial throat partial laryngectomy and total laryngectomy in T3 stage. Methods: The clinical data of 112 patients with stage T3 laryngeal carcinoma were retrospectively analyzed from January 1984 to May 1996. Among them, 48 cases of laryngectomy (29 cases were simple surgery and 19 cases were treated with radiotherapy) ; Total laryngectomy 64 cases (39 cases of simple surgery, surgery and radiotherapy 25 cases). Results The 3-year and 5-year survival rates of the laryngectomy group and the laryngectomy group were 77.1%, 66.7% and 97.7%, 71.1% respectively. The 3-year and 5-year survival rates The annual survival rates were 75.7%, 65.0% and 78.9%, 62.9% in the laryngectomy group and 81.2%, 71.4% and 76.0% and 70.6% in the laryngectomy group, respectively There was no significant difference in the annual and 5-year survival rates (P> 0.05). Conclusions: T3 laryngeal carcinoma has the same curative effect as laryngectomy as long as indications of laryngectomy are available. Postoperative radiotherapy can not reduce the risk of local and cervical cancer recurrence