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人体日本血吸虫感染的病理学不如曼氏血吸虫感染的那么明确。对日本血吸虫病的描述常假借曼氏血吸虫病的研究结果。急性毒血症性日本血吸虫病(片山热)在流行区出生的人中很少见,但常见于外来人口首次感染者。慢性重度感染的主要损害为肝脏的门脉周围纤维化伴脾肿大与门脉高压。在一些肝纤维化病例可见肺动脉炎与肺原性心脏病。如同曼氏血吸虫感染,在流行地区的人群中大多为无明显病理变化的轻型患者。
The pathology of human Schistosoma japonicum infection is not as clear as that of Schistosoma mansoni. The description of Japanese schistosomiasis often borrows from the results of Schistosoma mansoni research. Acute septic shock of Japanese schistosomiasis (Kathan fever) is rare in people born in endemic areas, but is common in first-time infected persons. Chronic severe infections of the main damage to the liver around the portal vein fibrosis with splenomegaly and portal hypertension. In some cases of liver fibrosis, pulmonary arteritis and pulmonary heart disease can be seen. As with Schistosoma mansoni, most of the people in the endemic areas are light-weight patients with no significant pathological changes.