钩端螺旋体病(简称钩体病)是由致病性钩体引起的一种自然疫源性疾病。在我国大多数省、市、区有本病存在和流行。解放后,对钩体病防治研究工作取得很大的成绩。现将钩体病流行病学研究近况综述如下。一、流行概况钩体病的分布很广泛,几乎全世界各国都有此病的存在和流行。在我国已有二十五个省、市、区有本病流行,尤以广东、云南、四川比较严重。在四川(1972～1974)发病率为13.84～20.56/10万,广西(1974)发病率为10.51/10万,湖南(1974)流行年发病率为12.29/10万,其他年份均在8.0/10万以下。在广东107个市县中病原学证实的82个,血清学 Leptospirosis (leptospirosis) is a naturally foci disease caused by the pathogenic leptospira. Most of our provinces, cities and districts have the existence and prevalence of the disease. After liberation, great achievements have been made in the research on prevention and treatment of leptospirosis. The current status of leptospirosis epidemiological studies are summarized below. First, the prevalence of leptospirosis distribution is very wide, almost all countries in the world have the existence and prevalence of the disease. Twenty-five provinces, cities and districts in our country have epidemics of this disease, especially in Guangdong, Yunnan and Sichuan. In Sichuan Province (1972 ~ 1974), the incidence rate was 13.84 ~ 20.56 / 100,000. The incidence rate in Guangxi (1974) was 10.51 / 100,000. The annual prevalence rate in Hunan (1974) was 12.29 / lakh and in other years it was 8.0 / 10 Below million. Etiology in 107 cities and counties in Guangdong confirmed 82, serological