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胃内定植是引起幽门螺杆菌(Helicobacter pylori,H.pylori)感染的先决条件。H.pylori可穿过胃黏液层并与胃上皮细胞相互作用。这个定植过程主要受到H.pylori动力和尿素酶的影响。同时H.pylori形态、胃内pH、外膜蛋白及益生菌等也在其中扮演重要角色。该研究主要对H.pylori胃内定植过程中的相关影响因素进行综述。
Stomach colonization is a prerequisite for infection with Helicobacter pylori (H. pylori). H. pylori can pass through the gastric mucus layer and interact with gastric epithelial cells. This colonization is mainly influenced by H.pylori dynamics and urease. At the same time, H.pylori morphology, gastric pH, outer membrane proteins and probiotics also play an important role. This study mainly reviewed the related factors of H.pylori intragastric colonization.